Mi-Kyung Kim Selected Research

4- (3- amino- 4- (2,4,5- trifluorophenyl)butanoyl)- 3- (tert- butoxymethyl)piperazin- 2- one

10/2020	Evogliptin, a dipeptidyl peptidase-4 inhibitor, attenuates pathological retinal angiogenesis by suppressing vascular endothelial growth factor-induced Arf6 activation.
12/2017	Unique binding mode of Evogliptin with human dipeptidyl peptidase IV.
2/2017	Prevention and treatment effect of evogliptin on hepatic steatosis in high-fat-fed animal models.
1/2016	Hepatic role in an early glucose-lowering effect by a novel dipeptidyl peptidase 4 inhibitor, evogliptin, in a rodent model of type 2 diabetes.
1/2012	DA-1229, a novel and potent DPP4 inhibitor, improves insulin resistance and delays the onset of diabetes.

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Mi-Kyung Kim Research Topics

Disease

18	Neoplasms (Cancer) 12/2022 - 12/2006
12	Type 2 Diabetes Mellitus (MODY) 01/2022 - 07/2011
11	Fibrosis (Cirrhosis) 10/2023 - 10/2009
11	Uterine Cervical Neoplasms (Cancer of the Cervix) 11/2021 - 12/2006
10	Inflammation (Inflammations) 10/2023 - 05/2011
9	Ovarian Neoplasms (Ovarian Cancer) 12/2019 - 01/2009
9	Insulin Resistance 01/2019 - 10/2008
8	Hyperglycemia 10/2023 - 01/2011
7	Carcinogenesis 03/2016 - 11/2009
6	Endometrial Neoplasms (Endometrial Cancer) 09/2023 - 01/2009
6	Ovarian Epithelial Carcinoma 07/2017 - 05/2009
5	Obesity 02/2023 - 08/2013
5	Carcinoma (Carcinomatosis) 07/2010 - 12/2002
4	Insulinoma 12/2021 - 10/2011
4	Body Weight (Weight, Body) 01/2021 - 01/2012
4	Breast Neoplasms (Breast Cancer) 01/2017 - 01/2009
3	Cardiovascular Diseases (Cardiovascular Disease) 02/2023 - 04/2004
3	Liver Cirrhosis (Hepatic Cirrhosis) 11/2019 - 03/2010
3	Fatty Liver 02/2017 - 01/2012
3	Hepatocellular Carcinoma (Hepatoma) 03/2016 - 10/2008
3	Hyperinsulinism (Hyperinsulinemia) 01/2014 - 09/2009
3	Abdominal Obesity 01/2014 - 04/2004
3	Uterine Cervical Dysplasia 06/2013 - 11/2009
2	Renal Cell Carcinoma (Grawitz Tumor) 04/2024 - 12/2002
2	Hypertension (High Blood Pressure) 10/2023 - 02/2023
2	Choriocarcinoma 09/2020 - 08/2015
2	Diabetic Nephropathies (Diabetic Nephropathy) 01/2019 - 01/2014
2	Liver Diseases (Liver Disease) 07/2018 - 09/2009
2	Glucose Intolerance 10/2017 - 01/2012
2	Weight Loss (Weight Reduction) 02/2017 - 01/2015
2	Uterine Hemorrhage (Uterine Bleeding) 08/2015 - 01/2009
2	Coronary Artery Disease (Coronary Atherosclerosis) 02/2014 - 06/2013
2	Atherosclerosis 01/2014 - 01/2013
2	Ureteral Obstruction 01/2012 - 10/2009

Drug/Important Bio-Agent (IBA)

15	Proteins (Proteins, Gene)FDA Link 09/2023 - 10/2009
10	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 10/2008
7	LipidsIBA 04/2024 - 10/2008
6	Dipeptidyl-Peptidase IV InhibitorsIBA 01/2022 - 01/2012
6	Insulin (Novolin)FDA Link 12/2021 - 10/2008
5	Biomarkers (Surrogate Marker)IBA 10/2023 - 01/2012
5	EnzymesIBA 10/2023 - 06/2013
5	4- (3- amino- 4- (2,4,5- trifluorophenyl)butanoyl)- 3- (tert- butoxymethyl)piperazin- 2- oneIBA 10/2020 - 01/2012
5	Plasminogen Activator Inhibitor 1IBA 01/2012 - 09/2009
4	CytokinesIBA 10/2023 - 07/2013
4	AntioxidantsIBA 01/2012 - 01/2009
4	Vitamin A (Retinol)FDA LinkGeneric 10/2010 - 01/2009
3	Triglycerides (Triacylglycerol)IBA 01/2020 - 06/2011
3	ClusterinIBA 11/2019 - 01/2012
3	Blood Glucose (Blood Sugar)IBA 01/2019 - 01/2015
3	Transforming Growth Factor beta (TGF-beta)IBA 10/2017 - 10/2009
3	Indicators and Reagents (Reagents)IBA 01/2017 - 01/2014
3	Orphan Nuclear ReceptorsIBA 03/2016 - 10/2009
3	Exenatide (Byetta)FDA Link 01/2015 - 07/2011
3	Glucagon-Like Peptide-1 ReceptorIBA 01/2015 - 10/2011
3	Fibronectins (Fibronectin)IBA 07/2014 - 10/2009
3	Angiotensin IIIBA 01/2014 - 12/2009
3	Cadherins (E-Cadherin)IBA 06/2013 - 12/2002
3	Oncogene Proteins (Oncogene Protein)IBA 06/2013 - 12/2010
3	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2011 - 10/2008
3	ZeaxanthinsIBA 11/2009 - 01/2009
3	LycopeneIBA 11/2009 - 01/2009
3	MicronutrientsIBA 11/2009 - 01/2009
3	alpha-Tocopherol FDA Link 11/2009 - 01/2009
3	LuteinIBA 11/2009 - 01/2009
3	gamma-TocopherolIBA 11/2009 - 01/2009
3	beta Carotene (Betacarotene)FDA Link 11/2009 - 01/2009
2	DA-1241IBA 10/2023 - 12/2021
2	Metformin (Glucophage)FDA LinkGeneric 01/2022 - 01/2014
2	lobeglitazoneIBA 01/2022 - 05/2019
2	Hormones (Hormone)IBA 01/2021 - 06/2013
2	Hypoglycemic Agents (Hypoglycemics)IBA 01/2021 - 01/2014
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2020 - 06/2013
2	Messenger RNA (mRNA)IBA 12/2019 - 02/2010
2	Thioacetamide (Thioacetamid)IBA 11/2019 - 10/2017
2	Interleukin-4 (Interleukin 4)IBA 01/2019 - 09/2016
2	SirtuinsIBA 01/2019 - 10/2017
2	kahweolIBA 07/2018 - 10/2017
2	Extracellular Matrix ProteinsIBA 12/2016 - 10/2009
2	ChromatinIBA 11/2015 - 01/2014
2	ThapsigarginIBA 01/2015 - 02/2010
2	ParaffinIBA 08/2014 - 12/2006
2	Cytochrome P-450 CYP2E1 (CYP2E1)IBA 07/2014 - 01/2012
2	Methionine (L-Methionine)FDA Link 07/2014 - 01/2012
2	Choline (Choline Chloride)IBA 07/2014 - 01/2012
2	Cilostazol (Pletal)FDA LinkGeneric 01/2014 - 12/2009
2	Liver X ReceptorsIBA 01/2014 - 05/2013
2	Sterol Regulatory Element Binding Protein 1IBA 01/2014 - 05/2013
2	AdipokinesIBA 07/2013 - 06/2011
2	SteroidsIBA 06/2013 - 01/2010
2	Thioctic Acid (Lipoic Acid)IBA 01/2012 - 03/2010
2	PlatinumIBA 01/2012 - 12/2006
2	Collagen Type I (Type I Collagen)IBA 01/2012 - 10/2009
2	Plasminogen Activators (Plasminogen Activator)IBA 01/2012 - 09/2009
2	Superoxide DismutaseIBA 10/2010 - 11/2009

Therapy/Procedure

7	Therapeutics 12/2022 - 06/2002
5	Hysterectomy 09/2012 - 01/2009
4	Lymph Node Excision (Lymph Node Dissection) 01/2023 - 11/2010
3	Drug Therapy (Chemotherapy) 09/2020 - 07/2011
3	Ligation 11/2019 - 01/2009
2	Adjuvant Chemotherapy 07/2017 - 11/2015